TOP TEN perturbations for P20142 (Homo sapiens)

Organism: Homo sapiens
Gene: P20142
Selected probe(set): 205261_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of P20142 (205261_at) across 5610 perturbations tested by GENEVESTIGATOR:

MALT lymphoma study 1 / normal spleen tissue

Relative Expression (log2-ratio):6.2682257
Number of Samples:8 / 6
Experimental MALT lymphoma study 1
Human t(11;18)-negative mucosa-associated lymphoid tissue (MALT) lymphoma cells.
Control normal spleen tissue
Normal human spleen tissue sample.

pancreatic cancer study 3 (ipmc) / pancreatic cancer study 3 (ipma)

Relative Expression (log2-ratio):-5.7194242
Number of Samples:6 / 6
Experimental pancreatic cancer study 3 (ipmc)
Intraductal papillary mucinous carcinoma from patients with pancreatic cancer.
Control pancreatic cancer study 3 (ipma)
Intraductal papillary mucinous adenoma from patients with pancreatic cancer.

pancreatic cancer study 3 (ipmn) / pancreatic cancer study 3 (ipma)

Relative Expression (log2-ratio):-5.617155
Number of Samples:3 / 6
Experimental pancreatic cancer study 3 (ipmn)
Intraductal papillary mucinous neoplasm from patients with pancreatic cancer.
Control pancreatic cancer study 3 (ipma)
Intraductal papillary mucinous adenoma from patients with pancreatic cancer.

hepatocyte (ESC) / Hep-G2

Relative Expression (log2-ratio):-5.029169
Number of Samples:8 / 9
Experimental hepatocyte (ESC)
Hepatocyte-like cells differentiated from embryonic stem cells (ESC)
Control Hep-G2
Human primary cancer cell line derived from the liver of a patient with hepatocellular carcinoma. Synonyms:HEP-G2; Hep G2; HEP G2; HepG2; HEPG2 Cellosaurus code:

lung adenocarcinoma study 3 (positive) / normal lung tissue

Relative Expression (log2-ratio):-4.8088703
Number of Samples:7 / 3
Experimental lung adenocarcinoma study 3 (positive)
Primary lung adenocarcinoma samples, with bone marrow positive for early disseminated tumor cells (DTCs). The presence of DTCs can predict the subsequent occurrence of overt metastasis and survival in lung cancer.
Control normal lung tissue
Normal lung tissue.

lung squamous cell carcinoma study 1 / normal lung tissue

Relative Expression (log2-ratio):-4.542159
Number of Samples:31 / 44
Experimental lung squamous cell carcinoma study 1
Primary lung squamous cell carcinoma samples of a patient with non-small cell lung cancer.
Control normal lung tissue
Histologically normal lung tissue.

gastric cancer study 1 (MSI) / adjacent gastric mucosa tissue

Relative Expression (log2-ratio):-4.425148
Number of Samples:19 / 29
Experimental gastric cancer study 1 (MSI)
Tumor biopsies from patients with microsatellite instability (MSI) gastric cancer.
Control adjacent gastric mucosa tissue
Adjacent normal tissue biopsies from patients with gastric cancer.

Hep-G2 / HepaRG

Relative Expression (log2-ratio):4.400653
Number of Samples:9 / 12
Experimental Hep-G2
Human primary cancer cell line derived from the liver of a patient with hepatocellular carcinoma. Synonyms:HEP-G2; Hep G2; HEP G2; HepG2; HEPG2 Cellosaurus code:
Control HepaRG
Immortalized cancer cell line derived from female patient with hepatocellular carcinoma. Cells can be induced to differentiate into hepatocyte-like cells by exposure to DMSO. Synonyms:Hepa-RG Cellosaurus code:

pancreatic cancer study 3 (ipma) / normal pancreas tissue

Relative Expression (log2-ratio):4.3438206
Number of Samples:6 / 6
Experimental pancreatic cancer study 3 (ipma)
Intraductal papillary mucinous adenoma from patients with pancreatic cancer.
Control normal pancreas tissue
Normal human pancreatic tissue.

HCC study 18 (very advanced) / HCC study 18 (very early)

Relative Expression (log2-ratio):4.2166853
Number of Samples:3 / 5
Experimental HCC study 18 (very advanced)
Tumor tissue samples obtained from liver of patients with very advanced hepatocellular carcinoma (HCC) undergoing resection or liver transplantation. Very advanced HCC cases included moderately to poorly differentiated tumors with macrovascular invasion or diffuse liver involvement. Patients positive for HBV markers, with history of alcohol consumption, nonalcoholic steatohepatitis, hemochromatosis, other chronic liver diseases or prior locoregional treatment were excluded.
Control HCC study 18 (very early)
Tumor tissue samples obtained from liver of patients with very early hepatocellular carcinoma (HCC) undergoing resection or liver transplantation. Very early HCC cases included well-differentiated tumors measuring ≤2 cm in diameter with no vascular invasion/satellites (size range: 8-20 mm). Patients positive for HBV markers, with history of alcohol consumption, nonalcoholic steatohepatitis, hemochromatosis, other chronic liver diseases or prior locoregional treatment were excluded.