TOP TEN perturbations for P43357 (Homo sapiens)

Organism: Homo sapiens
Gene: P43357
Selected probe(set): 209942_x_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of P43357 (209942_x_at) across 5610 perturbations tested by GENEVESTIGATOR:

glioma study 16 (LN-18) / normal astrocyte sample

Relative Expression (log2-ratio):9.763586
Number of Samples:2 / 3
Experimental glioma study 16 (LN-18)
Human glioma cell line LN018 was cultured in DMEM supplemented with 10% FCS (fetal calf serum) and antibiotics at 37C and 5% CO2.
Control normal astrocyte sample
Normal brain astrocytes. Clonetics normal human astrocytes (NHA) from Cambrex (primary-derived cultures) and cultured according to the manufacturer's recommendations.

glioma study 16 (LN-229) / normal astrocyte sample

Relative Expression (log2-ratio):9.294188
Number of Samples:2 / 3
Experimental glioma study 16 (LN-229)
Human glioma cell line LN229 was cultured in DMEM supplemented with 10% FCS (fetal calf serum) and antibiotics at 37?C and 5% CO2.
Control normal astrocyte sample
Normal brain astrocytes. Clonetics normal human astrocytes (NHA) from Cambrex (primary-derived cultures) and cultured according to the manufacturer's recommendations.

glioma study 16 (LN-215) / normal astrocyte sample

Relative Expression (log2-ratio):9.006033
Number of Samples:2 / 3
Experimental glioma study 16 (LN-215)
Human glioma cell line LN215 was cultured in DMEM supplemented with 10% FCS (fetal calf serum) and antibiotics at 37?C and 5% CO2.
Control normal astrocyte sample
Normal brain astrocytes. Clonetics normal human astrocytes (NHA) from Cambrex (primary-derived cultures) and cultured according to the manufacturer's recommendations.

AsPC-1 / BxPC-3

Relative Expression (log2-ratio):-8.600503
Number of Samples:3 / 3
Experimental AsPC-1
Human xenograft derived metastatic cancer cell line derived from mouse xenografts initiated with metastatic cells from the ascites derived from a 62 years old female Caucasian patient with pancreatic adenocarcinoma. Synonyms:AsPc-1; Aspc-1; ASPC-1; As-PC1; ASPC1; AsPC1; Aspc1; AsPc1 Cellosaurus code:
Control BxPC-3
Human pancreatic adenocarcinoma cell line derived from a 61 years old female patient. Synonyms:BxPc-3; BXPC-3; Bx-PC3; BXPC3; BxPC3; BxPc3 Cellosaurus code:

hepatocyte (ESC) / HepaRG

Relative Expression (log2-ratio):-7.9855576
Number of Samples:8 / 12
Experimental hepatocyte (ESC)
Hepatocyte-like cells differentiated from embryonic stem cells (ESC)
Control HepaRG
Immortalized cancer cell line derived from female patient with hepatocellular carcinoma. Cells can be induced to differentiate into hepatocyte-like cells by exposure to DMSO. Synonyms:Hepa-RG Cellosaurus code:

L3.6pl / COLO 357/FG

Relative Expression (log2-ratio):-7.0263643
Number of Samples:3 / 3
Experimental L3.6pl
Human, xenograft derived, pancreatic carcinoma cell line with high metastatic potential. The cell line is derived from liver metastases formed in mouse xenograft model. The mouse was originally injected with L3.3 pancreatic carcinoma cell line. Parental cell line:: COLO 357 Synonyms:L3.6PL; L3_6PL; L3.6 pancreas-liver; Colo357L3.6pl Cellosaurus code:
Control COLO 357/FG
Human, xenograft derived, pancreatic carcinoma cell line with low metastatic potential. The cell line is derived from unknown metastatic site of mouse xenograft model. The mouse was originally injected with COLO357 human pancreatic adenocarcinoma cell line. Parental cell line:: COLO 357 Synonyms:FG; Colo 357 FG; COLO 357 Fast Growing; Colo 357/FG; Colo357FG; COLO357FG; FG/COLO357 Cellosaurus code:

melanoma study 1 / normal skin tissue

Relative Expression (log2-ratio):6.466916
Number of Samples:3 / 4
Experimental melanoma study 1
Skin tissue from melanoma patients.
Control normal skin tissue
Normal skin tissue.

Hep-G2 / HepaRG

Relative Expression (log2-ratio):-6.4548197
Number of Samples:9 / 12
Experimental Hep-G2
Human primary cancer cell line derived from the liver of a patient with hepatocellular carcinoma. Synonyms:HEP-G2; Hep G2; HEP G2; HepG2; HEPG2 Cellosaurus code:
Control HepaRG
Immortalized cancer cell line derived from female patient with hepatocellular carcinoma. Cells can be induced to differentiate into hepatocyte-like cells by exposure to DMSO. Synonyms:Hepa-RG Cellosaurus code:

OVCAR-8 RIIB / OVCAR-8

Relative Expression (log2-ratio):6.117133
Number of Samples:3 / 3
Experimental OVCAR-8 RIIB
Human metastatic cancer cell line derived from the ascites fluid from a cisplatin-resistant patient with carcinoma of the ovary. Stably transfected with the cAMP-dependent protein kinase (PKA) regulatory subunit gene for RII?. Parental cell line:: OVCAR-8 Cellosaurus code:
Control OVCAR-8
Human metastatic cancer cell line derived from the ascites fluid from a cisplatin-resistant patient with carcinoma of the ovary. Synonyms:NIH:OVCAR-8; OVCAR8; Ovcar8; OVCAR.8; OVCA8 Cellosaurus code:

male infertility study 1 (mJS5) / male infertility study 1 (mJS2)

Relative Expression (log2-ratio):5.7275596
Number of Samples:8 / 7
Experimental male infertility study 1 (mJS5)
Human testicular lobules biopsy samples isolated from adult infertile patients whose seminiferous tubules contained spermatocytes but no spermatids. Tissue samples were classified based on modified Johnsen score (mJS) as mJS5.
Control male infertility study 1 (mJS2)
Human testicular lobules biopsy samples isolated from adult infertile patients whose seminiferous tubules contained almost exclusively Sertoli cells. Tissue samples were classified based on modified Johnsen score (mJS) as mJS2.