TOP TEN perturbations for Q96RI9 (Homo sapiens)

Organism: Homo sapiens
Gene: Q96RI9
Selected probe(set): 1553066_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of Q96RI9 (1553066_at) across 5880 perturbations tested by GENEVESTIGATOR:

retina pigment epithelium study 1 (adult) / retina pigment epithelium study 1 (fetal)

Relative Expression (log2-ratio):1.1251426
Number of Samples:2 / 6
Experimental retina pigment epithelium study 1 (adult)
Postmortem human native retina pigment epithelium samples from adult individuals.
Control retina pigment epithelium study 1 (fetal)
Human native fetal retina pigment epithelium samples obtained at gestation age between week 16-18.

connective/soft tissue cancer study 1 (PDX; connective and soft tissue, sarcoma, NOS; metastatic) / connective/soft tissue cancer study 1 (PDX; connective and soft tissue, clear cell sarcoma, NOS; metastatic)

Relative Expression (log2-ratio):-0.99794865
Number of Samples:3 / 2
Experimental connective/soft tissue cancer study 1 (PDX; connective and soft tissue, sarcoma, NOS; metastatic)
Patient-derived xenograft (PDX) samples generated in female athymic nude mice from a metastasis of patients with primary connective and soft tissue, sarcoma, NOS of the soft tissue (subcutaneously implanted). Metastatic site of patient tumor sample is not reported.
Control connective/soft tissue cancer study 1 (PDX; connective and soft tissue, clear cell sarcoma, NOS; metastatic)
Patient-derived xenograft (PDX) samples generated in female athymic nude mice from a metastasis of patients with primary connective and soft tissue, clear cell sarcoma, NOS of the soft tissue (subcutaneously implanted). Metastatic site of patient tumor sample is not reported.

basal cell carcinoma study 2 / normal skin tissue

Relative Expression (log2-ratio):0.97971153
Number of Samples:2 / 64
Experimental basal cell carcinoma study 2
Primary tumor tissue from the skin of patients with basal cell carcinoma (BCC).
Control normal skin tissue
Normal skin samples from healthy donors.

engineered skin substitute study 2 (intermediate) / engineered skin substitute study 1 (intermediate)

Relative Expression (log2-ratio):0.9589348
Number of Samples:6 / 3
Experimental engineered skin substitute study 2 (intermediate)
Human skin substitutes tissue samples collected after 14 and 28 days after transplantation to athymic mice.
Control engineered skin substitute study 1 (intermediate)
Human skin substitutes tissue samples collected after 7 days in culture.

Dengue hemorrhagic fever study 1 (6-10d) / Dengue fever study 6 (late)

Relative Expression (log2-ratio):0.93992996
Number of Samples:11 / 11
Experimental Dengue hemorrhagic fever study 1 (6-10d)
Peripheral blood mononuclear cell (PBMC) samples derived from the blood of Venezuelan individuals 6 – 10 days after the onset of Dengue hemorrhagic fever.
Control Dengue fever study 6 (late)
Peripheral blood mononuclear cell (PBMC) samples derived from the blood of Venezuelan individuals 6 to 10 days after the onset of Dengue fever.

medulloblastoma study 2 / non-tumor brain tissue

Relative Expression (log2-ratio):0.9133377
Number of Samples:4 / 9
Experimental medulloblastoma study 2
Primary tumor tissue sample from the infratentorial brain of pediatric patients with large-cell anaplastic medulloblastoma.
Control non-tumor brain tissue
Histologically normal brain tissue at rapid autopsy from patients who died from atypical teratoid/rhabdoid tumor.

Merkel cell carcinoma study 3 (metastatic) / normal skin tissue

Relative Expression (log2-ratio):0.8142605
Number of Samples:22 / 64
Experimental Merkel cell carcinoma study 3 (metastatic)
Metastatic tumor tissue from different metastatic sites (skin, lymph node, parotid gland) of patients with Merkel cell carcinoma of the skin.
Control normal skin tissue
Normal skin samples from healthy donors.

glioma study 17 (glioblastoma; unsorted) / non-tumor cortical tissue

Relative Expression (log2-ratio):-0.8008957
Number of Samples:2 / 4
Experimental glioma study 17 (glioblastoma; unsorted)
Brain cells isolated from high grade glioblastoma (grade IV). Tumor tissue was dissociated using enzymatic treatment and all cells were used for RNA isolation.
Control non-tumor cortical tissue
Cortical tissue obtained from patients with epilepsy, but without any manifested brain cancer. The tissue was dissociated using enzymatic treatment, but all brain cell types were used for analyses.

Dengue hemorrhagic fever study 1 (6-10d) / Dengue fever study 1 (convalescent)

Relative Expression (log2-ratio):0.7631674
Number of Samples:11 / 11
Experimental Dengue hemorrhagic fever study 1 (6-10d)
Peripheral blood mononuclear cell (PBMC) samples derived from the blood of Venezuelan individuals 6 – 10 days after the onset of Dengue hemorrhagic fever.
Control Dengue fever study 1 (convalescent)
Peripheral blood mononuclear cell (PBMC) samples derived from the blood of Venezuelan individuals 28 days after the onset of Dengue fever.

skin squamous cell carcinoma study 6 / normal skin tissue

Relative Expression (log2-ratio):0.75179386
Number of Samples:4 / 64
Experimental skin squamous cell carcinoma study 6
Primary tumor tissue from the skin of patients with squamous cell carcinoma (SCC).
Control normal skin tissue
Normal skin samples from healthy donors.