TOP TEN perturbations for Q9HCR9 (Homo sapiens)

Organism: Homo sapiens
Gene: Q9HCR9
Selected probe(set): 237248_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of Q9HCR9 (237248_at) across 5392 perturbations tested by GENEVESTIGATOR:

HCC827 / A-549

Relative Expression (log2-ratio):-4.685904
Number of Samples:6 / 6
Experimental HCC827
Human primary cancer cell line derived from the lung of a patient with non-small-cell lung cancer. Synonyms:HCC-827; HCC0827 Cellosaurus code:
Control A-549
Human primary cancer cell line derived from the lung of a patient with carcinoma. Synonyms:A 549; A549; NCI-A549; A549/ATCC; hA549 Cellosaurus code:

glioma study 16 (secondary glioblastoma) / normal brain tissue

Relative Expression (log2-ratio):-3.9346552
Number of Samples:3 / 2
Experimental glioma study 16 (secondary glioblastoma)
Secondary glioma tissues obtained from the operating room. Tumors were diagnosed and graded according to the current WHO classification (grade IV).
Control normal brain tissue
Normal brain tissue sample from healthy donors.

glycogen storage disease type II study 1 / normal biceps tissue

Relative Expression (log2-ratio):-3.7718973
Number of Samples:8 / 10
Experimental glycogen storage disease type II study 1
Biceps femoris muscle biopsy sample from patients with infantile onset Morbus Pompe (Pompe disease).
Control normal biceps tissue
Biceps femoris biopsy muscle samples from control subjects.

TGF-? study 10 / untreated A549 cell sample

Relative Expression (log2-ratio):3.59583
Number of Samples:3 / 3
Experimental TGF-? study 10
A549 cells were cultured for 2-3 weeks in the presence of 2ng/ml of TGF-?, to induce epithelial-mesenchymal transition (EMT). 24 hours prior analysis cells were re-seeded without TGF-?.
Control untreated A549 cell sample
A549 cells grown in standard media.

influenza virus study 9 (A/pH1N1) / influenza virus study 4 (A/H1N1)

Relative Expression (log2-ratio):3.3248959
Number of Samples:3 / 3
Experimental influenza virus study 9 (A/pH1N1)
Human carcinoma cell line A549 infected with influenza A virus subtype [A/Singapore/478/2009 (pH1N1)]. Samples were taken 10 hours post-infection.
Control influenza virus study 4 (A/H1N1)
Human carcinoma cell line A549 infected with influenza A virus subtype A/WSN/33 (H1N1). Samples were taken 10 hours post-infection.

glioma study 16 (oligodendroglioma) / normal brain tissue

Relative Expression (log2-ratio):-3.2902594
Number of Samples:7 / 2
Experimental glioma study 16 (oligodendroglioma)
Primary oligodendroglioma tissues obtained from the operating room. Tumors were diagnosed and graded according to the current WHO classification (grade OGII-III).
Control normal brain tissue
Normal brain tissue sample from healthy donors.

glioma study 16 (astrocytoma) / normal brain tissue

Relative Expression (log2-ratio):-3.2312336
Number of Samples:8 / 2
Experimental glioma study 16 (astrocytoma)
Primary astrocytoma tissues obtained from the operating room. Tumors were diagnosed and graded according to the current WHO classification (grade III-IV).
Control normal brain tissue
Normal brain tissue sample from healthy donors.

glioma study 17 (glioblastoma; unsorted) / non-tumor cortical tissue

Relative Expression (log2-ratio):-2.9569187
Number of Samples:2 / 4
Experimental glioma study 17 (glioblastoma; unsorted)
Brain cells isolated from high grade glioblastoma (grade IV). Tumor tissue was dissociated using enzymatic treatment and all cells were used for RNA isolation.
Control non-tumor cortical tissue
Cortical tissue obtained from patients with epilepsy, but without any manifested brain cancer. The tissue was dissociated using enzymatic treatment, but all brain cell types were used for analyses.

glioma study 16 (glioblastoma) / normal brain tissue

Relative Expression (log2-ratio):-2.8015585
Number of Samples:12 / 2
Experimental glioma study 16 (glioblastoma)
Primary glioma tissues obtained from the operating room. Tumors were diagnosed and graded according to the current WHO classification (grade IV).
Control normal brain tissue
Normal brain tissue sample from healthy donors.

ovarian tumor study 19 (FIGO IIIb) / ovarian tumor study 19

Relative Expression (log2-ratio):-2.7794266
Number of Samples:7 / 2
Experimental ovarian tumor study 19 (FIGO IIIb)
Ovarian tissue samples from female patient with primary serous cystadenocarcinoma. Staging of the disease was assessed according to the criteria of the FIGO and patients from this group were staged as FIGO IIIb.
Control ovarian tumor study 19
Ovarian tissue samples from female patient with primary serous cystadenocarcinoma.