TOP TEN perturbations for Q9UKY0 (Homo sapiens)

Organism: Homo sapiens
Gene: Q9UKY0
Selected probe(set): 222106_at
Platform: Affymetrix Human Genome U133 Plus 2.0 Array

Expression of Q9UKY0 (222106_at) across 5610 perturbations tested by GENEVESTIGATOR:

exercise study 37 (OUT; post-exerc.) / exercise study 37 (OT; pre-exerc.)

Relative Expression (log2-ratio):-4.0704417
Number of Samples:12 / 12
Experimental exercise study 37 (OUT; post-exerc.)
Vastus lateralis muscle biopsy sample from old, untrained (OUT) subjects (>80 years old) participating in a 12 weeks progressive resistance training (PRT). Sample was taken 4 hours after the first resistance exercise unit of the progressive resistance training.
Control exercise study 37 (OT; pre-exerc.)
Vastus lateralis muscle biopsy sample from old, untrained (OUT) subjects (>80 years old) participating in a 12 weeks progressive resistance training (PRT). Sample was taken before the last exercise unit of the progressive resistance training.

atypical teratoid/rhabdoid tumor study 1 / non-tumor brain tissue

Relative Expression (log2-ratio):3.637177
Number of Samples:20 / 9
Experimental atypical teratoid/rhabdoid tumor study 1
Primary tumor tissue sample from the brain of pediatric patients with atypical teratoid/rhabdoid tumor (AT/RT).
Control non-tumor brain tissue
Histologically normal brain tissue at rapid autopsy from patients who died from atypical teratoid/rhabdoid tumor.

atypical teratoid/rhabdoid tumor study 1 / medulloblastoma study 2

Relative Expression (log2-ratio):3.6155677
Number of Samples:20 / 4
Experimental atypical teratoid/rhabdoid tumor study 1
Primary tumor tissue sample from the brain of pediatric patients with atypical teratoid/rhabdoid tumor (AT/RT).
Control medulloblastoma study 2
Primary tumor tissue sample from the infratentorial brain of pediatric patients with large-cell anaplastic medulloblastoma.

atypical teratoid/rhabdoid tumor study 1 / primitive neuroectodermal tumor study 1

Relative Expression (log2-ratio):3.5406876
Number of Samples:20 / 9
Experimental atypical teratoid/rhabdoid tumor study 1
Primary tumor tissue sample from the brain of pediatric patients with atypical teratoid/rhabdoid tumor (AT/RT).
Control primitive neuroectodermal tumor study 1
Primary tumor tissue sample from the supratentorial brain of pediatric patients with primitive neuroectodermal tumor.

exercise study 33 (OT; fast twitch; post-exerc.) / exercise study 33 (OUT; fast twitch; post-exerc.)

Relative Expression (log2-ratio):3.4987602
Number of Samples:4 / 3
Experimental exercise study 33 (OT; fast twitch; post-exerc.)
Fast twitch myosin heavy chain muscle fibers (MHC) IIa were obtained from vastus lateralis muscle. Biopsies were taken from old trained (OT) women (85?1 years) 4 hours after the 36th (last) exercise session. Participants underwent 12 weeks of progressive resistance training including 36 training sessions (3 days/week) with three sets of 10 bilateral knee extensions at 70?75% of their one-repetition maximum (1 RM). Fibers were separated under the light microscope and MHC isoform was determinated based on SDS-PAGE analysis. Exclusion criteria: acute/chronic illness, cardiac, pulmonary, liver, or kidney abnormalities, uncontrolled hypertension, insulin or non-insulin-dependent diabetes, abnormal blood, or urine chemistries, arthritis, a history of neuromuscular problems, tobacco smoking. Individuals, that had ever completed any formal exercise programs or physical activity outside of their activities of daily living, were excluded as well.
Control exercise study 33 (OUT; fast twitch; post-exerc.)
Fast twitch myosin heavy chain muscle fibers (MHC) IIa were obtained from vastus lateralis muscle. Biopsies were taken from old untrained (OUT) women (85?1 years) 4 hours after the first resistance exercise. Fibers were separated under the light microscope and MHC isoform was determinated based on SDS-PAGE analysis. Exclusion criteria: acute/chronic illness, cardiac, pulmonary, liver, or kidney abnormalities, uncontrolled hypertension, insulin or non-insulin-dependent diabetes, abnormal blood, or urine chemistries, arthritis, a history of neuromuscular problems, tobacco smoking. Individuals, that had ever completed any formal exercise programs or physical activity outside of their activities of daily living, were excluded as well.

atypical teratoid/rhabdoid tumor study 1 / glioma study 5

Relative Expression (log2-ratio):3.355257
Number of Samples:20 / 12
Experimental atypical teratoid/rhabdoid tumor study 1
Primary tumor tissue sample from the brain of pediatric patients with atypical teratoid/rhabdoid tumor (AT/RT).
Control glioma study 5
Primary tumor tissue sample from the supratentorial brain of pediatric patients with glioblastoma multiformae.

exercise study 37 (YUT; post-exerc.) / exercise study 37 (YT; pre-exerc.)

Relative Expression (log2-ratio):-3.1547108
Number of Samples:16 / 15
Experimental exercise study 37 (YUT; post-exerc.)
Vastus lateralis muscle biopsy sample from young, untrained (YUT) subjects (20-30 years old) participating in a 12 weeks progressive resistance training (PRT). Sample was taken 4 hours after the first resistance exercise unit of the progressive resistance training.
Control exercise study 37 (YT; pre-exerc.)
Vastus lateralis muscle biopsy sample from young, trained (YT) subjects (20-30 years old) participating in a 12 weeks progressive resistance training (PRT). Sample was taken before the last exercise unit of the progressive resistance training.

exercise study 37 (OT; post-exerc.) / exercise study 37 (OUT; pre-exerc.)

Relative Expression (log2-ratio):3.1153312
Number of Samples:12 / 12
Experimental exercise study 37 (OT; post-exerc.)
Vastus lateralis muscle biopsy sample from old, untrained (OUT) subjects (>80 years old) participating in a 12 weeks progressive resistance training (PRT). Sample was taken 4 hours after the last resistance exercise unit of the progressive resistance training.
Control exercise study 37 (OUT; pre-exerc.)
Vastus lateralis muscle biopsy sample from old, untrained (OUT) subjects (>80 years old) participating in a 12 weeks progressive resistance training (PRT). Sample was taken before the first exercise unit of the progressive resistance training.

atypical teratoid/rhabdoid tumor study 1 / medulloblastoma study 1

Relative Expression (log2-ratio):3.069003
Number of Samples:20 / 17
Experimental atypical teratoid/rhabdoid tumor study 1
Primary tumor tissue sample from the brain of pediatric patients with atypical teratoid/rhabdoid tumor (AT/RT).
Control medulloblastoma study 1
Primary tumor tissue sample from the infratentorial brain of pediatric patients with classical medulloblastoma.

breast cancer study 42 (metastase; lymph node) / breast cancer study 42 (metastase; chest wall)

Relative Expression (log2-ratio):-3.0307188
Number of Samples:7 / 2
Experimental breast cancer study 42 (metastase; lymph node)
Metastatic tumor tissue obtained from the lymph node of patients with primary breast adenocarcinoma.
Control breast cancer study 42 (metastase; chest wall)
Metastatic tumor tissue obtained from the chest wall of patients with primary breast adenocarcinoma.