TOP TEN perturbations for Q6YND2 (Mus musculus)

Organism: Mus musculus
Gene: Q6YND2
Selected probe(set): 1435481_at
Platform: Affymetrix Mouse Genome 430 2.0 Array

Expression of Q6YND2 (1435481_at) across 2700 perturbations tested by GENEVESTIGATOR:

PNS cell type study 1 (E16, SG) / PNS cell type study 1 (E12, SG)

Relative Expression (log2-ratio):2.1909704
Number of Samples:4 / 3
Experimental PNS cell type study 1 (E16, SG)
Neurons from cochlear spiral ganglion (SG) were isolated from embryonic day 16 (E16) mice using FACS based on EGFP fluorescence.
Control PNS cell type study 1 (E12, SG)
Neurons from cochlear spiral ganglion (SG) were isolated from embryonic day 12 (E12) mice using microdissection based on GFP fluorescence.

testis development study 7 (P14) / testis development study 7 (P0)

Relative Expression (log2-ratio):1.8150578
Number of Samples:2 / 2
Experimental testis development study 7 (P14)
Testis tissue isolated from wildtype mice at postnatal day P14.
Control testis development study 7 (P0)
Testis tissue isolated from wildtype mice at postnatal day P0.

PNS cell type study 1 (E16, SG) / PNS cell type study 1 (E13, SG)

Relative Expression (log2-ratio):1.8049402
Number of Samples:4 / 3
Experimental PNS cell type study 1 (E16, SG)
Neurons from cochlear spiral ganglion (SG) were isolated from embryonic day 16 (E16) mice using FACS based on EGFP fluorescence.
Control PNS cell type study 1 (E13, SG)
Neurons from cochlear spiral ganglion (SG) were isolated from embryonic day 13 (E13) mice using microdissection based on GFP fluorescence.

oocyte maturation study 1 (MII) / oocyte maturation study 1 (GV)

Relative Expression (log2-ratio):-1.6346436
Number of Samples:3 / 3
Experimental oocyte maturation study 1 (MII)
Mature oocytes isolated at MII stage of their maturation. Oocytes were harvested from 22-24 days old wildtype hybrid females of B6SJLF1 genetic background.
Control oocyte maturation study 1 (GV)
Fully grown oocytes isolated at GV stage of their maturation. Oocytes were harvested from 22-24 days old wildtype hybrid females of B6SJLF1 genetic background.

testis development study 7 (P14) / testis development study 7 (P3)

Relative Expression (log2-ratio):1.5667496
Number of Samples:2 / 2
Experimental testis development study 7 (P14)
Testis tissue isolated from wildtype mice at postnatal day P14.
Control testis development study 7 (P3)
Testis tissue isolated from wildtype mice at postnatal day P3.

glucose study 1 (3mM; young) / fresh pancreatic islet (C57BL/6; young)

Relative Expression (log2-ratio):1.4795055
Number of Samples:2 / 2
Experimental glucose study 1 (3mM; young)
Pancreatic islets isolated from 5 weeks old C57BL/6 mice cultured for 2 days in RPMI media containing 3mM glucose. Islets were isolated by collagenase digestion and a Histopaque gradient and allowed to recover over night in RPMI media containing 11 mM glucose, 10% FCS and penicillin/streptomycin.
Control fresh pancreatic islet (C57BL/6; young)
Pancreatic islets freshly isolated from 5 weeks old (young) C57BL/6 mice. Islets were isolated by collagenase digestion and a Histopaque gradient.

basket cells study 1 (P56) / basket cells study 1 (P14)

Relative Expression (log2-ratio):-1.3984222
Number of Samples:2 / 4
Experimental basket cells study 1 (P56)
Basket cells were isolated from CB6-Tg(Gad1-EGFP)G42Zjh/J mouse strain. These cells were manually sorted from the cerebellum of a 56-days-old mouse (P56) based on EGFP fluorescence, shape, size and localization. The numbers of cells were from 125 to 150.
Control basket cells study 1 (P14)
Basket cells were isolated from CB6-Tg(Gad1-EGFP)G42Zjh/J mouse strain. These cells were manually sorted from the cerebellum of a 14-days-old mouse (P14) based on EGFP fluorescence, shape, size and localization. The numbers of cells were from 125 to 150.

krill oil study 1 / normal liver tissue (CBA/J)

Relative Expression (log2-ratio):-1.3946142
Number of Samples:7 / 7
Experimental krill oil study 1
Liver obtained from wild-type male mice (CBA/J, 5 months old) fed AIN-93M-krill oil diet for 3 months. AIN-93M diet was modified by an equivalent amount substitution of the soy bean oil with 1.5% of krill oil. The content of docosahexaenoic acid (DHA) was 0.11 g per 100g of diet and the amount of eicosapentaenoic acid was 0.19 g per 100g of diet. Mice were euthanized by cervical dislocation after an overnight fast.
Control normal liver tissue (CBA/J)
Liver obtained from wild-type male mice (CBA/J, 5 months old) maintained on the control diet based on AIN-93M diet (containing 4% lipid from soybean oil) for 3 months. Mice were euthanized by cervical dislocation after an overnight fast.

testis development study 7 (P18) / testis development study 7 (P0)

Relative Expression (log2-ratio):1.3722639
Number of Samples:2 / 2
Experimental testis development study 7 (P18)
Testis tissue isolated from wildtype mice at postnatal day P18.
Control testis development study 7 (P0)
Testis tissue isolated from wildtype mice at postnatal day P0.

Purkinje cells study 1 (P28) / Purkinje cells study 1 (P3)

Relative Expression (log2-ratio):-1.3645773
Number of Samples:3 / 3
Experimental Purkinje cells study 1 (P28)
Purkinje cells were isolated from CB6-Tg(Gad1-EGFP)G42Zjh/J mouse strain. These cells were manually sorted from the cerebellum of a 28-days-old mouse study 1 (P28) based on EGFP fluorescence, shape, size and localization. The numbers of cells were from 50 to 75.
Control Purkinje cells study 1 (P3)
Purkinje cells were isolated from CB6-Tg(Gad1-EGFP)G42Zjh/J mouse strain. These cells were manually sorted from the cerebellum of a 3-days-old mouse (P3) based on EGFP fluorescence, shape, size and localization. The numbers of cells were from 50 to 75.