TOP TEN perturbations for Q4G078 (Rattus norvegicus)
Organism: Rattus norvegicus
Gene: Q4G078
Selected probe(set): 1382085_at
Platform: Affymetrix Rat Genome 230 2.0 Array
Expression of Q4G078 (1382085_at) across 7639 perturbations tested by GENEVESTIGATOR:
anti-Mullerian hormone study 1 / cultured ovary tissue (Sprague Dawley)
Relative Expression (log2-ratio):-1.5711632Number of Samples:2 / 2
Experimental | anti-Mullerian hormone study 1 |
Ovary samples from 4 days old female Sprague Dawley rats cleaned of ovarian bursa and treated for 10 days in medium containing 500 ng/ml anti-Mullerian hormone (AMH). | |
Control | cultured ovary tissue (Sprague Dawley) |
Untreated ovary samples from 4 days old female Sprague Dawley rats cleaned of ovarian bursa and cultured for 10 days. |
TCDD study 5 (Wistar Han; 10d) / TCDD study 5 (Wistar Han; 4d)
Relative Expression (log2-ratio):1.3573608Number of Samples:5 / 4
Experimental | TCDD study 5 (Wistar Han; 10d) |
Liver samples from 11-15 weeks old TCDD-resistant Wistar Han (Kuopio) male rats treated with compound: TCDD (2,3,7,8-tetrachlorodibenzo-p-dioxin; 100 ug/kg; vehicle: corn oil) for 10 days. ATC code:--- | |
Control | TCDD study 5 (Wistar Han; 4d) |
Liver samples from 11-15 weeks old TCDD-resistant Wistar Han (Kuopio) male rats treated with compound: TCDD (2,3,7,8-tetrachlorodibenzo-p-dioxin; 100 ug/kg; vehicle: corn oil) for 4 days. ATC code:--- |
pirinixic acid (WY-14643) study 7 (100mg/kg) / vehicle treated (corn oil) liver tissue samples (Crj:CD(SD)IGS)
Relative Expression (log2-ratio):1.3273048Number of Samples:3 / 3
Experimental | pirinixic acid (WY-14643) study 7 (100mg/kg) |
Liver samples derived from 6 weeks old male Crj:CD(SD)IGS rats, treated with compound: WY-14643 (100mg/kg; CHEMBL295416). Rats were treated by gavage once daily for 7 days and sacrificed 24 hours after the last treatment. ATC code:--- | |
Control | vehicle treated (corn oil) liver tissue samples (Crj:CD(SD)IGS) |
Liver samples derived from 6 weeks old male Crj:CD(SD)IGS rats, treated with vehicle (corn oil). Rats were treated by gavage once daily for 7 days and sacrificed 24 hours after the last treatment. |
TCDD study 5 (T-LE; 10d) / TCDD study 5 (Wistar Han; 10d)
Relative Expression (log2-ratio):-1.2927437Number of Samples:5 / 5
Experimental | TCDD study 5 (T-LE; 10d) |
Liver samples from 11-15 weeks old TCDD-sensitive Long Evans (Turku/AB) male rats treated with compound: TCDD (2,3,7,8-tetrachlorodibenzo-p-dioxin; 100 ug/kg; vehicle: corn oil) for 10 days. ATC code:--- | |
Control | TCDD study 5 (Wistar Han; 10d) |
Liver samples from 11-15 weeks old TCDD-resistant Wistar Han (Kuopio) male rats treated with compound: TCDD (2,3,7,8-tetrachlorodibenzo-p-dioxin; 100 ug/kg; vehicle: corn oil) for 10 days. ATC code:--- |
ethionine study 12 (250mg/kg) / vehicle treated (0.5% methylcellulose) liver tissue samples (Crj:CD(SD)IGS)
Relative Expression (log2-ratio):1.2811003Number of Samples:3 / 3
Experimental | ethionine study 12 (250mg/kg) |
Liver samples derived from 6 weeks old male Crj:CD(SD)IGS rats, treated with compound: ethionine (250mg/kg; CHEMBL203187). Rats were treated by gavage once daily for 28 days and sacrificed 24 hours after the last treatment. ATC code:--- | |
Control | vehicle treated (0.5% methylcellulose) liver tissue samples (Crj:CD(SD)IGS) |
Liver samples derived from 6 weeks old male Crj:CD(SD)IGS rats, treated with vehicle (0.5% methylcellulose). Rats were treated by gavage once daily for 28 days and sacrificed 24 hours after the last treatment. |
carboplatin study 19 (600uM) / vehicle treated (medium) hepatocyte samples (Sprague Dawley)
Relative Expression (log2-ratio):1.2591839Number of Samples:2 / 2
Experimental | carboplatin study 19 (600uM) |
Hepatocyte samples derived from 6 weeks old male Sprague Dawley rats, treated with compound: carboplatin (600uM; CHEMBL288376). Hepatocytes were treated for 24 hours. ATC code: | |
Control | vehicle treated (medium) hepatocyte samples (Sprague Dawley) |
Hepatocyte samples derived from 6 weeks old male Sprague Dawley rats, treated with vehicle (medium). Hepatocytes were vehicle treated for 24 hours. |
kidney development study 3 (eng. kid. tissue) / kidney development study 3 (E13)
Relative Expression (log2-ratio):-1.2267513Number of Samples:2 / 3
Experimental | kidney development study 3 (eng. kid. tissue) |
Engineered kidney tissue created by recombining an in vitro budded Wolffian duct (WD) with fresh E13 metanephric mesenchyme (MM). Non-branched in vitro-formed ureteric buds (UBs) were dissected from the extracellular matrix gel (ECM) after 7-10 days of cultivation and then placed in contact with freshly isolated MM (isolated from kidneys at E13.5). Afterwards the recombination was co-cultured on a transfilter for another 6 days in DMEM/F12 plus 10% FCS. The urogenital tract was isolated from timed pregnant Holtzman rats. | |
Control | kidney development study 3 (E13) |
Kidney tissue isolated from rat (unspecified strain) at the embryonic day 13. |
ethionine study 19 (2000uM) / vehicle treated (medium) hepatocyte samples (Sprague Dawley)
Relative Expression (log2-ratio):1.2264271Number of Samples:2 / 2
Experimental | ethionine study 19 (2000uM) |
Hepatocyte samples derived from 6 weeks old male Sprague Dawley rats, treated with compound: ethionine (2000uM; CHEMBL203187). Hepatocytes were treated for 24 hours. ATC code:--- | |
Control | vehicle treated (medium) hepatocyte samples (Sprague Dawley) |
Hepatocyte samples derived from 6 weeks old male Sprague Dawley rats, treated with vehicle (medium). Hepatocytes were vehicle treated for 24 hours. |
3Y1-B clone 1-MUC1 / 3Y1-B clone 1-con
Relative Expression (log2-ratio):1.1983414Number of Samples:2 / 2
Experimental | 3Y1-B clone 1-MUC1 |
Rat 3Y1-B clone 1 embryonic fibroblast culture cell line stably transfected with an expression vector expressing the cytoplasmic domain of the oncoprotein MUC1p. Synonyms:3Y1/MUC1-CD Parental cell line:: Rat 3Y1-B clone 1 | |
Control | 3Y1-B clone 1-con |
Rat 3Y1-B clone 1 embryonic fibroblast modified by stable control transfection. Parental cell line:: Rat 3Y1-B clone 1 |
ethionine study 19 (10000uM) / vehicle treated (medium) hepatocyte samples (Sprague Dawley)
Relative Expression (log2-ratio):1.1624212Number of Samples:2 / 2
Experimental | ethionine study 19 (10000uM) |
Hepatocyte samples derived from 6 weeks old male Sprague Dawley rats, treated with compound: ethionine (10000uM; CHEMBL203187). Hepatocytes were treated for 24 hours. ATC code:--- | |
Control | vehicle treated (medium) hepatocyte samples (Sprague Dawley) |
Hepatocyte samples derived from 6 weeks old male Sprague Dawley rats, treated with vehicle (medium). Hepatocytes were vehicle treated for 24 hours. |